Professional microneedling serums

Professional Microneedling Serums

Professional microneedling serums formulated specifically for use during and after microneedling treatments.

This page exists to explain what professional microneedling serums are, how they differ from cosmetic skincare and how to choose formulations that are compatible with microneedling.

Professional microneedling treatment using a sterile serum in a clinical setting


What Makes a Microneedling Serum “Professional”

Microneedling serums are not the same as everyday skincare. When the skin barrier is intentionally disrupted, formulation standards change.

Professional microneedling serums are designed specifically for skin that is being actively treated or has just been treated. They prioritize tolerance, purity, controlled glide, and compatibility with open skin rather than texture enhancers, fragrance or cosmetic additives.

As microneedling has grown in popularity, imitation products have entered the market. Many appear professional but are not formulated or tested for microneedling conditions. Lumni formulations are created specifically for microneedling contexts, not repurposed skincare.

What Is a Microneedling Serum?

A microneedling serum is a formulation intended to be applied during and/or immediately after microneedling treatments, when micro-channels are present in the skin.

Unlike traditional skincare serums, microneedling serums are designed to:

  • Minimize irritation on compromised skin
  • Support controlled delivery of functional ingredients
  • Avoid unnecessary sensitizers and cosmetic fillers
  • Maintain proper slip and spread during treatment

This distinction is critical for both treatment safety and outcomes.

Why Regular Skincare Serums Are Not Suitable for Microneedling

Most cosmetic serums are formulated for intact skin. When used during microneedling, they can introduce unnecessary risk.

Common issues with standard skincare serums include:

Fragrance or essential oils
Harsh or cosmetic-grade preservatives
Fillers that provide texture but no treatment benefit
Actives not intended for open or compromised skin

Professional microneedling serums are formulated with microneedling conditions in mind, not daily cosmetic use.

Ingredients Considered Suitable for Microneedling

Ingredients used in professional microneedling serums are selected for how they behave on treated skin — not just for marketing appeal.

  • Hyaluronic acid for hydration, slip, and delivery support
  • Select peptides formulated for specific treatment goals
  • Supportive compounds chosen for tolerance and compatibility

Lumni uses hyaluronic acid as a foundational base because it:

  • Supports glide during microneedling
  • Helps maintain hydration during treatment
  • Acts as a stable base for targeted actives

Why Different Microneedling Serums Exist

There is no single “best” microneedling serum for every situation. Different formulations exist to support different treatment outcomes.

  • Treatment glide and hydration support
  • Rejuvenation and skin renewal goals
  • Elasticity and firmness support
  • Skin brightening support
  • Collagen support

Professional protocols rely on selecting the right serum for the right stage of treatment.

Lumni Professional Microneedling Serums

Lumni formulates professional microneedling serums with a singular focus: compatibility with microneedling treatments.

Each serum is developed to serve a specific role during or after microneedling, without unnecessary additives or cosmetic fillers.

→ View all Professional Microneedling Serums

Professional Standards and Transparency

Microneedling serums are not medical injectables, but truly professional formulations are held to a higher standard than everyday cosmetic skincare.

Reputable brands are transparent about how their products are made and tested. You should always be able to request a Certificate of Analysis (COA). If a provider cannot supply one, there is a strong possibility the product has not been lab tested and may contain contaminants or inconsistent ingredients.

Depending on formulation and classification, professional microneedling serums may be:

  • Lab tested for quality and purity
  • Produced in controlled environments
  • Designed to reduce contamination risk during open-skin treatments

The rise in microneedling demand has also led to knockoff products that look professional but do not meet professional formulation standards. Lumni does not cut corners.

Always choose products intended specifically for microneedling — not shortcuts made to look the part.